The purpose of this study was to assess the cortical-level sensory differences between natural teeth with a periodontal membrane and dental implants.
We used functional near-infrared spectroscopy (fNIRS) to measure brain activity in the cerebral cortex of 12 patients who had both natural teeth and dental implants in the lower molar region. Painless vibratory tactile stimulation was performed on both the natural teeth and the dental implants.
Activation was seen in the somatosensory cortex during stimulation of both natural teeth and dental implants. A comparison of cortical activation showed no significant differences between natural teeth and dental implants.
These results indicate the possible existence of sensory input to the cerebral cortex via dental implants as well as natural teeth, and thus suggest that may not only the periodontal membrane be involved in the signaling pathway. The data from this experiment may help us for understanding the neural mechanisms underlying natural teeth and dental implants. fNIRS, natural teeth, implants, brain activity, somatosensory cortex.
These results indicate the possible existence of sensory input to the cerebral cortex via dental implants as well as natural teeth, and thus suggest that may not only the periodontal membrane be involved in the signaling pathway. The data from this experiment may help us for understanding the neural mechanisms underlying natural teeth and dental implants. Key wordsfNIRS, natural teeth, implants, brain activity, somatosensory cortex.Analysis of the anatomy of the region during preoperative planning is very important in order to minimize the risks of undesired movements in the supporting teeth or even damage to important structures such as the maxillary sinus. To the best of our knowledge, no study evaluated the relationship of these skeletal patterns with the anatomy of the infrazygomatic crest. The aim of this study was to evaluate the tomographic measurements of the infrazygomatic crest for placement of temporary anchorage devices in individuals with different vertical and sagittal skeletal patterns.
The measurements were analyzed in three regions in the crest of 67 patients above the maxillary first molar A slice in the long axis of the mesiobuccal root, a slice passing through the center of the furcation area of the tooth, and another slice in the long axis of the distobuccal root. In each of these slices five measurements of the thickness of the infrazygomatic crest were performed, with a difference of 1 mm between them. The sagittal skeletal pattern was determined by the ANB angle and the vertical skeletal pattern by the SN.GoGn angle.
The bone thickness of the crest tended to decrease gradually in the apical direction. There was no difference between different vertical and sagittal skeletal patterns.
The individual parameters did not have significant influence in the thickness of the infrazygomatic crest. Tomography, X-Ray Computed, orthodontics, mini-implant, infrazygomatic crest, maxilla.
The individual parameters did not have significant influence in the thickness of the infrazygomatic crest. Key wordsTomography, X-Ray Computed, orthodontics, mini-implant, infrazygomatic crest, maxilla.Mastication is the process of breaking ingested food with the teeth and mixing it with saliva to form a mass that is easy to swallow. However, few studies have reported on oral functions, such as occlusal force, tongue pressure, and mastication. The purpose of this study was to evaluate the association between masticatory function and oral functions, such as occlusal force and tongue pressure.
In this study, there were 113 patients (41 men and 72 women; mean age, 68.4 ± 11.3 years) who visited dentists at the Hiroshima University Hospital, Hiroshima, Japan between April 2015 and November 2018. Masticatory function of the patients was evaluated using a masticatory ability test system. In addition, occlusal force was measured using a pressure-sensitive film and the maximum tongue pressure was measured with a tongue pressure measuring device according to a conventional method. The relationship of masticatory ability with occlusal force and tongue pressure was examined using multivariate analysis while considering patients' age, gender, and the number of remaining teeth.
Masticatory ability was significantly related to occlusal force, maximum tongue pressure, age, body mass index, the number of remaining teeth, and occlusal contact area (&lt; 0.05). Multiple regression analysis identified that masticatory ability was significantly associated (&lt; 0.05) with occlusal force and maximum tongue pressure.
Masticatory ability was significantly associated with occlusal force and maximum tongue pressure, indicating that the large muscle mass in the oral cavity is indispensable for improving masticatory function. Mastication, tongue pressure, occlusion force, oral function.
Masticatory ability was significantly associated with occlusal force and maximum tongue pressure, indicating that the large muscle mass in the oral cavity is indispensable for improving masticatory function. Key wordsMastication, tongue pressure, occlusion force, oral function.Acclaimed as one of the biggest scientific breakthroughs, the technology of CRISPR has brought significant improvement in the biotechnological spectrum-from editing genetic defects in diseases for gene therapy to modifying organisms for the production of biofuels. Since its inception, the CRISPR-Cas9 system has become easier and more versatile to use. Many variants have been found, giving the CRISPR toolkit a great range that includes the activation and repression of genes aside from the previously known knockout and knockin of genes. Here, in this Perspective, we describe efforts on automating the gene-editing workflow, with particular emphasis given on the use of microfluidic technology. We discuss how automation can address the limitations of gene-editing and how the marriage between microfluidics and gene-editing will expand the application space of CRISPR.Coronavirus disease 2019 (COVID-19) has been shown to affect the cardiovascular system, and several cases of takotsubo syndrome (TTS) induced by COVID-19 have been reported. TTS predominantly affects postmenopausal women in western countries, but the prevalence in men is higher in Asian populations. It should be noted that male patients with either TTS or COVID-19 are associated with higher mortality. Despite the higher prevalence of TTS in Asian men, little is known about Asian men with TTS induced by COVID-19. This is a case report of a 60-year-old Asian male with biventricular TTS precipitated by COVID-19. https://www.selleckchem.com/products/vx-984.html He presented with acute respiratory distress syndrome, cardiogenic shock, and acute kidney injury. He required intubation, multiple vasopressors, and renal replacement therapy. The left ventricular ejection fraction was 15%, but it normalized in 5 weeks. The patient had a prolonged hospital stay in a critical condition, but was eventually discharged alive. The scarce literature about this condition in Asian male populations and the increasing number of COVID-19 cases in Asian countries highlight the rarity and importance of this case.